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347,348 Aging-related NAD + decline causes mitochondrial dysfunction Combining the evidence that mitochondrial dysfunction is a hallmark of aging and NAD + plays a crucial role in the maintenance of mitochondrial function

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For instance, pentadecapeptide BPC 157, by stimulating both expression of egr-1 and its repressor NAB2 (18), may represent a controlling mechanism that may be responsible for regulation of egr-1

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